Liver tumors also known as hepatocellular carcinoma (HCC) are caused by chronic infection with hepatitis C (HCV) and hepatitis B virus (HBV). HCV and HBV infection also leads to chronic liver disease and cirrhosis of liver. Other common causes associated with HCC is NASH (non-alcoholic steatohepatitis) seen in overweight and obese individual, and chronic alcohol ingestion leading to liver cirrhosis. Biliary tract cancer is caused by infestation with flukes Opisthorchis viverrini and Clonorchis sinensis and also biliary tract stone. Gall bladder cancer are most commonly caused by long standing gall stone. Pancreatic cancer in contrast is more commonly linked with genetic factor, although alcohol and smoking is found to be risk factor, no conclusive evidence found for it.