Surgery remains the corner stone of the treatment in thyroid malignancy. Surgery is either total or near total thyroidectomy. Enlarged neck nodes involved by tumors may require formal neck dissection. Post operative radio iodine treatment with I131 is required in locally advanced or metastatic disease. Thyroid replacement therapy required after total thyroidectomy.
Surgery is also the treatment of choice in parathyroid carcinoma, in large tumors of parathyroid may require excision of thyroid gland for enbloc removal of cancer. Management of calcium excess in body is difficult situation in metastatic or locally advanced parathyroid cancer.